Download e-book for kindle: Advances in Male Mediated Developmental Toxicity by Jack B. Bishop (auth.), Bernard Robaire, Barbara F. Hales

By Jack B. Bishop (auth.), Bernard Robaire, Barbara F. Hales (eds.)

ISBN-10: 1441991905

ISBN-13: 9781441991904

ISBN-10: 1461348293

ISBN-13: 9781461348290

This quantity highlights significant contributions that determine new advancements and instructions within the box over the last decade, in addition to demanding situations for the foreseeable destiny. An integration of data from laboratory and epidemiological experiences, male copy and teratology are available during the quantity. the variety of issues contain parental legacies and genomics, way of life, occupational and healing paternal exposures and results; results at the gamete-packaging of human sperm; position of DNA fix and germ mobile apoptosis; stem cells, epigenetics and shutting; version structures and implications to clinicians and common counselors.

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1998b). Further information on the outcome of clinically recognised pregnancies which were diagnosed during the six cycles of follow-up was collected by questionnaire and telephone interview. We obtained complete data on 183 pregnancies during the 6 months of follow-up.

1 to increased susceptibility to leukaemia or non-Hodgkin ' s lymphoma in children. , 1993) . In spite of the se negative surveys, the Gardner report was used in a civil court case on behalf of two of the alleged victims of paternal irradiation at Seascale against Briti sh Nuclear Fuel s (Wakeford and Tawn , 1994) . , 1994) . A survey by Parker et al. (1993) and parallel studies carried out by the HSE (1993 , 1994) corroborated this report - see also Draper et al. (1997) . Gardner acknowledged that pos sible expo sure to internally incorporated radionuclides had not been taken into account and such sources could possibly explain their findings.

After chemotherapy , males can be advised not to indulge in sexual practices for a few months, to allow progression of newly formed germ cells through the next spermatogenic cycle , and often males do not feel well enough to mate. Thus, the animal models might not exact ly reflect the human situation because animals are constantly mating. g. when interviewing for reproductive outcome. This can be illustrated by reproductive studies with vinyl chloride. Persona l interviews and/or questionnaires are a primary source of data for monitoring program mes.

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Advances in Male Mediated Developmental Toxicity by Jack B. Bishop (auth.), Bernard Robaire, Barbara F. Hales (eds.)


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